Gastrointestinal tract

Gastrointestinal tract

The mucous membranes of the gastrointestinal tract are frequently involved in patients with hereditary angioedema (HAE). In fact, it is estimates that more than 70% of the swellings suffered by HAE patients affect the mucous membranes of the internal organs.

Swelling attacks affecting the gastrointestinal tract typically manifest as:

  • Cramping, colicky pain
  • Nausea
  • Vomiting
  • Diarrhoea

In some cases, swelling attacks are limited to the internal organs and swellings of the skin are absent or develop later. In such cases, gastrointestinal symptoms may often be mistakenly attributed to other more common disorders, such as appendicitis or gastric ulcer. Because of this some undergo unnecessary surgical procedures.